NFRI-funded Grant Programs
Funds will be awarded to investigators dedicated to advancing NF-related MPNST research, identifying potential for the re-purposing of existing therapies for MPNST treatment, and collaborating with the NF research community to improve clinical treatment and patient outcomes related to MPNST.
All grants provided by the NF Research Initiative have a 10% indirect rate cap.
Current Awardees
2019 Companion Grant Program for MPNST Patient-Derived Model Testing
Angie Hirbe, MD, PhD - Data Coordinating Center at Washington University School of Medicine
David Largaespada, PhD - Model Development and Testing Center at University of Minnesota
The purpose of this grant program is to produce actionable pre-clinical data about response to single agent and combination agents using patient-derived NF1-related MPNST models such as PDX and organoids, with the goal of informing human clinical trials for NF1-related MPNST. These awards support a project similar to the National Cancer Institute’s PDX-net.